Anatabine Ameliorates Experimental Autoimmune Thyroiditis
نویسندگان
چکیده
منابع مشابه
Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine
Anatabine, a naturally occurring alkaloid, is becoming a commonly used human food supplement, taken for its claimed anti-inflammatory properties although this has not yet been reported in human clinical trials. We have previously shown that anatabine does display certain anti-inflammatory properties and readily crosses the blood-brain barrier suggesting it could represent an important compound ...
متن کاملEmodin Ameliorates Experimental Autoimmune Myocarditis
225 Received May 7, 2012; revision accepted for publication June 21, 2012. doi: 10.1620/tjem.227.225 Correspondence: Jian Hu, Department of Cardiology, The First Hospital of China Medical University, China Medical University, Heping District, 155 North Nanjing Street, Shenyang 110001, P.R. China. e-mail: [email protected] Emodin, a Naturally Occurring Anthraquinone, Ameliorates Experimental...
متن کاملResveratrol ameliorates experimental autoimmune myocarditis.
BACKGROUND Myosin-induced autoimmune myocarditis of rats is a model of human dilated cardiomyopathy. Resveratrol is a natural polyphenol found in grapes and wine that is reported to have cardioprotective and immunomodulatory effects. METHODS AND RESULTS To examine the effect of resveratrol on myocarditis, vehicle or resveratrol (50 mg/kg per day) was administered to cardiac myosin immunized r...
متن کاملBlocking GluR2–GAPDH ameliorates experimental autoimmune encephalomyelitis
OBJECTIVE Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. The pathophysiological mechanism of MS remains largely unknown and no cure is available. Current clinical treatments for MS modulate the immune system, with the rationale that autoimmunity is at the core of MS pathophysiology. METHODS Experimental autoimmune encephalitis (EAE) was induced in m...
متن کاملIL-12p40 Homodimer Ameliorates Experimental Autoimmune Arthritis.
IL-23 is the key cytokine that induces the expansion of Th17 cells. It is composed of p19 and p40 subunits of IL-12. The p40 subunit binds competitively to the receptor of IL-23 and blocks its activity. Our aim was to assess the preventive and therapeutic effect of the IL-12p40 homodimer (p40)2 subunit in autoimmune arthritis animal models. In the current study, using IL-1R antagonist-knockout ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Endocrinology
سال: 2012
ISSN: 0013-7227,1945-7170
DOI: 10.1210/en.2012-1452